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C8/SCX Column Plates for Solid Phase Extraction
The LabGo C8/SCX is a silica gel-based packing column with C8 and strong cation exchange SCX (C8/SCX) mixed in an optimal ratio to provide a dual containment mechanism in which the C8 functional group interacts with the hydrophobic analyte groups and the SCX functional group interacts with the protonated amino group. Due to such strong interactions, stronger wash conditions can be used to remove co-extracts that may interfere with UV detection or cause ion suppression in LC-MS. The steady-state phase is not capped, allowing for additional interactions between the residual silanol groups and the polar analytes, thereby contributing to improved retention.
Most suitable for purification of basic (cationic) or neutral compounds such as drugs and metabolites from aqueous solutions, urine and blood.
Equivalent to Agilent Bond Elut Certify and Phenomenex
Filler Information
- Substrate: silica gel
- Functional groups: octyl and quaternary ammonium salts
- Mechanism of action: reversed-phase extraction, strong anion exchange
- Particle size: 40-75μm
- Surface area: 510 m2/g
Application
Soil; water; body fluids (plasma/urine, etc.); Food; petroleum.
Typical Applications The C8/SCX functional group consists of proportionally bound octyl and sulfonic acid groups with a double retention effect: the octyl group provides moderate hydrophobicity and the sulfonic acid group provides strong cation exchange.
For samples that are difficult to elute due to excessive adsorption of C18 and C8 as well as excessive retention of SCX, a C8/SCX mixed mode column can be used.
Order Details
| Filler | type | norm | Packing (/bag) | Product Number |
| C8/SCX | Column | 100mg/1ml | 100 | SPEC8SCX130 |
| 200mg/3ml | 50 | SPEC8SCX1100 | ||
| 500mg/3ml | 50 | SPEC8SCX3200 | ||
| 500mg/6ml | 30 | SPEC8SCX3500 | ||
| 1g/6ml | 30 | SPEC8SCX6200 | ||
| 1g/12ml | 20 | SPEC8SCX6500 | ||
| 2g/12ml | 20 | SPEC8SCX61000 | ||
| Plate | 96×50mg | 96-well | SPEC8SCX121000 | |
| 96×100mg | 96-well | SPEC8SCX122000 | ||
| 384×10mg | 384-well | SPEC8SCX9650 | ||
| Filler | 100g | ваза | SPEC8SCX96100 |
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